Monday, 26th of January at 11:30 am
Welcome by: Aoife Gahlawat, Sabine Baumgart, Bertram Bengsch, Desiree Kunkel, Axel Schulz, Sarah Warth
Meeting host: Aoife Gahlawat, DKFZ & NCT Heidelberg
Welcome talk by Denis Schapiro
Institute for Computational Biomedicine and Institute of Pathology
Heidelberg University Hospital
Abstract
Quantitative tissue analysis at the Translational Spatial Profiling Center (TSPC)
In this talk, I will introduce our recently founded Translational Spatial Profiling Center (TSPC) and the computational tools we are developing to enable robust and high-throughput analysis of a variety of highly multiplexed spatial technologies for proteomics (antibody-based) and transcriptomics. I will also introduce our spatial power analysis framework for improved experimental design strategies and for neighborhood method benchmarking. Finally, I will highlight how we utilized the developed tools to process data with use cases in oncology and cardiology.
Biosketch
Dr. Denis Schapiro is Acting Director of the Institute for Computational Biomedicine and Research Group Leader at the Medical Faculty of the Heidelberg University, Managing Director of the Translational Spatial Profiling Center (TSPC) and Adjunct IFOM Group Leader focusing on spatial omics technologies and analysis. He is also a co-founder and the current president of the European Society for Spatial Biology (ESSB) e.V.