Thursday, 25th of January 2024 at 11:45 am – 12:30 pm
Chair: Henrik Mei
Noel de Miranda
Department of Pathology, Leiden University Medical Center, the Netherlands
Charting the Cancer Battlefield: Unraveling Tumor Microenvironments and Immunotherapy Dynamics
State-of-the-art multidimensional technologies have revolutionized our comprehension of tumor microenvironments, revealing their complex composition and dynamic behaviors. The integration of a spatial dimension has been pivotal in examining cell-to-cell interactions and characterizing cellular communities within landscape of tumor microenvironments.
In my presentation, I will showcase how imaging mass cytometry, either independently or synergistically with other cutting-edge technologies, has significantly enhanced our knowledge of immune mechanisms in cancer. Its application is not only enriching our understanding of tumor microenvironments but it has also to refine and support the development of effective immunotherapeutic strategies for cancer treatment.
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Dr. de Miranda is an expert in cancer genetics and immunology at the Leiden University Medical Center. His research group employs cutting-edge genomic, transcriptomic, and proteomic technologies, including single cell and spatial analysis, to investigate the genetic and immunological aspects of cancer. His main goal is to facilitate the development of innovative immunotherapies to expand the range of therapeutic options available for treating cancer patients.